Saturday, 25 July 2020

Friedel Crafts Acylation - toluene?

Elmo Tervo: Yes, but you need a special twist to the Friedel-Crafts acylation. In the real world, formyl chloride (the part that you would add on to benzene) is too unstable, and it has to be made "in situ" by adding carbon monoxide and HCl. However, if this is for a homework assignment, your teacher might be satisfied if you propose a regular Friedel-Crafts acylation.

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